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2010—2012年中国城市成年居民血清总胆固醇状况
作者:宋鹏坤 李红 贾珊珊 满青青 李丽祥 赵丽云 张坚

摘要:

目的  分析2010—2012年中国城市成年居民血清总胆固醇(TC)水平、高TC血症及TC边缘升高状况。方法  数据来自2010—2012年中国居民营养与健康状况监测。采用多阶段分层与人口成比例的整群随机抽样方法抽样,调查对象为我国34个大城市和41个中小城市18岁以上居民,共54 042名。采用胆固醇氧化酶法测定血TC。按《中国成人血脂异常防治指南》2007版进行高TC血症和TC边缘升高诊断标准进行分析。采用2009年国家统计局公布的人口数据,进行复杂抽样加权处理,计算TC水平(),以及高TC血症、TC边缘升高率及95%CI值。结果  中国城市成年居民血清TC水平为(4.58±0.05)mmol/L,男性和女性均为(4.58±0.05)mmol/L;大城市为(4.66±0.04)mmol/L,中小城市为(4.57±0.06)mmol/L。18~69岁成年居民血清TC水平随年龄的增长有逐渐升高的趋势,18~29岁组为(4.18±0.05)mmol/L;60~69岁组最高,为(4.94±0.05)mmol/L;70岁以上组略有降低,为(4.92±0.06)mmol/L。中国城市成年居民高TC血症和TC边缘升高率分别为5.6%(95%CI:4.5%~6.6%)和24.7%(95%CI:21.6%~27.9%),男性为5.1%(95%CI:4.1%~6.1%)和24.4%(95%CI:21.0%~27.6%),女性为6.0%(95%CI:4.7%~7.3%)和25.1%(95%CI:21.8%~28.4%);大城市为6.0%(95%CI: 5.0%~7.0%)和27.7%(95%CI:24.9%~30.6%),中小城市为5.5%(95%CI:4.2%~6.7%)和24.2%(95% CI:20.5%~27.9%)。18~29岁年龄组TC血症患病率最低,为2.2%(95%CI:1.4%~3.0%),70岁以上组患病率最高,为10.3% (95%CI:7.1%~13.4%);18~29岁组TC边缘升高率最低,为12.9% (95%CI: 10.4%~15.4%),60~69岁组患病率最高,为37.6%(95%CI:33.6%~41.6%)。结论  2010—2012年中国城市成年居民血清TC水平、高TC血症及TC边缘升高率均较高,城市老年人群血清TC水平在各年龄组最高,需要重点关注。

关键词:胆固醇;成年人;中国;横断面研究

Abstract:

Objective  To analyze the serum total cholesterol level and the prevalence of hypercholesterolemia and borderline high cholesterolemia among urban-resident adults in China from 2010 to 2012.Methods  Data were from Chinese Nutrition and Health Surveillance in 2010-2012. Multi-stage stratified proportion to the population cluster random sampling method was conducted to determine 54 042 adult residents in 34 big cities and 41 small and medium-sized cities. Serum total cholesterol was measured by cholesterol oxidase method. Hypercholesterolemia and borderline high cholesterolemia were evaluated by Guidelines on Prevention and Treatment of Blood Lipid Abnormality in Chinese Adults 2007 edition. Standardized cholesterol level () and prevalence of hypercholesterolemia and borderline high cholesterolemia were calculated through weighted complex sampling processing by population data released by the National Bureau of Statistics in 2009.Results  The mean level of urban-resident adults's erum total cholesterol was (4.58±0.05)mmol/L, (4.58±0.05)mmol/L for both male and female. The cholesterol concentration level in big cities and small and medium-sized cities were (4.66±0.04)mmol/L and (4.57±0.06) mmol/L, respectively. It increased with age gradually from the minimum level, which was (4.18±0.05)mmol/L in aged 18 to 29 group, till reached the maximum, which was (4.94±0.05)mmol/L in aged 60 to 69 group, and then it declined to (4.92±0.06)mmol/L in aged 70 group. The prevalence of hypercholesterolemia and borderline high cholesterolemia were 5.6%(95%CI:4.5%-6.6%) and 24.7%(95%CI:21.6%-27.9%) totally; 5.1% (95%CI:4.1%-6.1%) and 24.4% (95%CI:21.0%-27.6%) for male, 6.0% (95%CI:4.7%-7.3%) and 25.1%(95%CI:21.8%-28.4%) for female; 6.0%(95%CI: 5.0%-7.0%) and 27.7%(95%CI:24.9%-30.6%) in big cities, while 5.5%(95%CI: 4.2%-6.7%) and 24.2%(95%CI:20.5%-27.9%) in small and medium-sized cities. The minimum prevalence of hypercholesterolemia was in aged 18 to 29 group and maximum in aged 70 group, which were 2.2%(95%CI: 1.4%-3.0%) and 10.3%(95%CI: 7.1%-13.4%), respectively; while the lowest borderline high cholesterolemia prevalence was in aged 18 to 29 group and the highest in aged 60 to 69 year group, which were 12.9%(95%CI: 10.4%-15.4%) and 37.6% (95%CI: 33.6%-41.6%), respectively.Conclusion  The serum total cholesterol level and the prevalence of hypercholesterolemia and borderline high cholesterolemia were high among urban adults in China from 2010 to 2012, and more attention should be paid for high serum total cholesterol level among older adults.

Key words: Cholesterol;Adult;China;Cross-sectional studies

发表日期:2016/3

引用本文:

图/表:

  • 10.3760/cma.j.issn.0253-9624.2016.03.003.T001:表1 调查对象年龄、性别及地区分布情况(n)

    10.3760/cma.j.issn.0253-9624.2016.03.003.T001:表1 调查对象年龄、性别及地区分布情况(n)

  • 10.3760/cma.j.issn.0253-9624.2016.03.003.T002:表2 2010—2012年中国城市成年居民血清TC水平(mmol/L,)

    10.3760/cma.j.issn.0253-9624.2016.03.003.T002:表2 2010—2012年中国城市成年居民血清TC水平(mmol/L,)

  • 10.3760/cma.j.issn.0253-9624.2016.03.003.T003:表3 2010—2012年中国城市成年居民高TC血症患病率[%(95%CI)]

    10.3760/cma.j.issn.0253-9624.2016.03.003.T003:表3 2010—2012年中国城市成年居民高TC血症患病率[%(95%CI)]

  • 10.3760/cma.j.issn.0253-9624.2016.03.003.T004:表4 2010—2012年中国城市成年居民TC边缘升高率[%(95%CI)]

    10.3760/cma.j.issn.0253-9624.2016.03.003.T004:表4 2010—2012年中国城市成年居民TC边缘升高率[%(95%CI)]

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