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2011年山东省18~69岁居民血脂异常流行状况
作者:张吉玉 唐俊利 郭晓雷 董静 任杰 陈希 高丛丛 徐爱强

摘要:

目的  分析山东省18~69岁居民血脂异常的流行特征。方法  于2011年7月,采用多阶段分层整群随机抽样方法在山东省140个市(区)进行调查,选取18~69岁常住人口(居住时间6个月以上)为调查对象,共15 350名。抽取空腹静脉血5 ml,检测其TC、LDL-C、HDL-C和TG。对样本进行复杂加权后,计算总的血脂异常以及高TC血症、高LDL-C血症、低HDL-C血症及高TG血症患病率,并采用复杂抽样加权方法对血脂异常患病率等指标进行统计学调整。采用χ2检验比较不同特征调查对象高TC血症、高LDL-C血症、低HDL-C血症及高TG血症患病率差异。结果  15 350名调查对象中,血脂总异常率为22.70%(3 572例),其中男性异常率为26.91%(2 110/7 683),高于女性[18.41%(1 462/7 667)](χ2=157.89,P<0.001)。高TC血症患病率为3.39%(582例),鲁东地区较高,为4.59%(185/3 704)。高LDL-C血症患病率为0.56%(94例),鲁东地区较高,为0.79%(32/3 704)。低HDL-C血症患病率为11.41%(1 789例)。高TG血症患病率为13.02%(2 059例),城市居民患病率为16.54%(814/4 804),高于农村[11.52%(1 245/10 546)](χ2= 71.54,P<0.001)。鲁东、鲁中南和鲁西北地区居民低HDL-C血症和高TG血症患病率差异均无统计学意义。结论  山东省成年居民血脂异常水平较高,男性患病率高于女性;鲁东地区居民高TC血症和高LDL-C血症患病率均高于其他地区;血脂异常类型以高TG和低HDL-C为主。

关键词:成年人;血脂异常;横断面研究

Abstract:

Objective  To investigate the prevalence and distribution characteristics of dyslipidemia among Shandong residents aged 18-69 years.Methods  The levels of triglyceride (TG), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and total cholesterol (TC) were determined in fasting serum of 5 ml venous blood for subjects aged 18-69 years who were selected by multi-stage stratified cluster random sampling from 20 counties in July, 2011 in 140 counties of Shandong province. The prevalence of dyslipidemia, hypercholesterolemia, high blood LDL-C, low blood HDL-C and hypertriglyceridemia were analyzed by the complex weighting. The prevalence of dyslipidemia, hypercholesterolemia, high blood LDL-C, low blood HDL-C and hypertriglyceridemia were compared for different characteristics by Rao-Scott χ2.Results  The prevalence of dyslipidemia among 15 350 subjects was 22.70% (3 572), with higher in males (26.91% (2 110/7 683)) than in females (18.41% (1 462/7 667)). The prevalence of hypercholesterolemia was 3.39% (n=582), with higher in Eastern Shandong (4.59% (185/3 704)). The prevalence of high blood LDL-C was 0.56% (n=94), with higher in Eastern Shandong (0.79% (32/3 074)). The prevalence of low blood HDL-C was 11.41% (n=1 789). The prevalence of hypertriglyceridemia was 13.02% (n=2 059), higher in urban residents (16.54% (814/4 804)) than in rural (11.52% (1 245/10 546)) (χ2=71.54, P<0.001). The difference between the prevalence of low blood HDL-C and hypertriglyceridemia was not significant among Eastern Shandong, Central-South and Northwest.Conclusion  Dyslipidemia rate was higher among adult residents in Shandong province. The rate was higher for men than for women. The prevalence of hypercholesterolemia and high blood LDL-C were higher in Eastern Shandong than the other areas. The hypertriglyceridemia and low blood HDL-C were two major types of dyslipidemia.

Key words: Adults;Dyslipidemias;Cross-section studies

发表日期:2016/3

引用本文:

图/表:

  • 10.3760/cma.j.issn.0253-9624.2016.03.008.T001:表1 调查对象的基本特征

    10.3760/cma.j.issn.0253-9624.2016.03.008.T001:表1 调查对象的基本特征

  • 10.3760/cma.j.issn.0253-9624.2016.03.008.T002:表2 调查对象年龄构成与2009年山东省常住人口年龄构成比较(%)

    10.3760/cma.j.issn.0253-9624.2016.03.008.T002:表2 调查对象年龄构成与2009年山东省常住人口年龄构成比较(%)

  • 10.3760/cma.j.issn.0253-9624.2016.03.008.T003:表3 山东省不同特征居民血脂异常情况比较[n(%)]

    10.3760/cma.j.issn.0253-9624.2016.03.008.T003:表3 山东省不同特征居民血脂异常情况比较[n(%)]

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