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齐齐哈尔市1 836名体检成年人骨骼肌量及其与年龄的关联研究
作者:王颖 宋永丽 孟丽苹 陈志刚 张莹 陈禹含 林丽荣 张玉伟 高巍 石岩萍

摘要:

目的  分析齐齐哈尔市体检成年人的骨骼肌含量及其与年龄的相关性。方法  选择2013年12月至2014年9月在齐齐哈尔市某医院参加体检的18~87岁成年人作为调查对象,排除患有冠心病、感染性疾病、内分泌疾病、高血压、贫血、癌症、肝肾疾病者及体内配带心脏起搏器者后,共计纳入1 836名对象。采用人体成分分析仪测定调查对象四肢骨骼肌量(ASM),计算相对骨骼肌质量指数(RSMI),应用线性回归分析法分析ASM、RSMI与年龄之间的关系。采用t检验比较不同性别调查对象身高、体重、BMI、腰臀比、总肌肉量、体脂百分比等指标的差异;采用多因素方差分析法分析不同性别调查对象各年龄组间四肢骨骼肌量及骨骼肌总量的差异;采用χ2检验比较不同性别调查对象各年龄组肌肉下降率的差异。结果  男性总肌肉量为(52.22±6.65) kg,高于女性[(38.05±4.39)kg](t=28.20,P<0.001)。18~29、30~39、40~49、50~59、60~69、70~87岁组男性四肢骨骼肌总量分别为(24.64±3.23)、(24.00±3.12)、(24.35±3.03)、(23.33±2.97)、(22.54±2.91)和(21.40±3.36)kg(F=16.12,P<0.001);女性分别为(16.48±3.14)、(16.72±1.93)、(16.75±1.93)、(16.84±2.28)、(16.52±2.35)和(14.70±2.37)kg(F=4.38,P=0.001)。男性四肢骨骼肌总量为(23.72±3.16)kg,高于女性[(16.65±2.25) kg](t=55.97, P<0.001)。50岁以后,男性ASM与年龄呈负相关,回归方程为y=28.31-0.09xP<0.001),而女性在60岁以后ASM与年龄呈负相关,回归方程为y=27.69-0.18xP<0.001)。女性骨骼肌肉量下降率为16.85%(124/736),高于男性(8.73%,96/1 100)(χ2=27.57,P<0.001)。结论  男性50岁以后,ASM与年龄呈负相关,而女性ASM在60岁以后与年龄呈负相关,且女性骨骼肌量下降率高于男性。

关键词:肌,骨骼;肌肉衰减征;电阻抗;年龄

Abstract:

Objective  To analyze the correlation between skeletal muscle mass and age among check-up adults.Methods  The study objects were those who aged 18-87 years old and came to a city hospital of Qiqihar for health examination from December, 2013 to September, 2014, excepted those with coronary heart disease, infectious disease, endocrine system disease, hypertension, anemia, cancer, liver disease, kidney disease and those carrying with heart pacemaker. A total of 1 836 respondents were finally enrolled into analysis. Appendicular Skeletal Muscle (ASM) was measured by a Body Composition Analyzer, and relative skeletal muscle index (RSMI) was calculated. The relationship among ASM, RSMI and age was assessed by linear regression analysis. The difference of height, weight, BMI, waist-hip-ratio (WHR), total muscle mass and percentage of body fat between genders were tested by t-test. The difference of ASM and total skeletal muscle mass between genders and among age groups was tested by multi-factor variance analysis. The difference of the muscle decline between genders was compared by Chi-square test.Results  The total muscle mass in males was (52.22±6.65) kg, which was significantly higher than that in females ((38.05±4.39) kg) (t=28.20, P<0.001). ASM in 18-29, 30-39, 40-49, 50-59, 60-69, 70-87 years was (24.64±3.23), (24.00±3.12), (24.35±3.03), (23.33±2.97), (22.54±2.91) and (21.40±3.36) kg (F=16.12, P<0.001) in males, respectively, and (16.48±3.14), (16.72±1.93), (16.75±1.93), (16.84±2.28), (16.52±2.35) and(14.70±2.37)kg (F=4.38, P=0.001) in females, respectively. ASM in males ((23.72±3.16) kg) was higher than that in females ((16.65±2.25) kg) (t=55.97, P<0.001). There was a negative correlation between age and ASM in males after 50 years old, the regression equation was y=28.31-0.09x (P<0.001). While a negative correlation between age and ASM in females occurred after 60 years old, the regression equation was y=27.69-0.18x (P<0.001). The prevalence of low ASM was 16.85% (124/736) in females, which was significantly higher than that in males (8.73%, 96/1 100) (χ2=27.57, P<0.001).Conclusion  A negative correlation was found between age and ASM in males after 50 years old and in females after 60 years old. The prevalence of low RSMI in females was significantly higher than that in males.

Key words: Muscle, skeleton;Sarcopenia;Electric impedance;Age

发表日期:2016/3

引用本文:

图/表:

  • 10.3760/cma.j.issn.0253-9624.2016.03.009.T001:表1 不同性别调查对象体检指标测量结果比较(±s,n=1 836)

    10.3760/cma.j.issn.0253-9624.2016.03.009.T001:表1 不同性别调查对象体检指标测量结果比较(±s,n=1 836)

  • 10.3760/cma.j.issn.0253-9624.2016.03.009.T002:表2 不同年龄调查对象四肢骨骼肌量比较(kg,±s)

    10.3760/cma.j.issn.0253-9624.2016.03.009.T002:表2 不同年龄调查对象四肢骨骼肌量比较(kg,±s)

  • 10.3760/cma.j.issn.0253-9624.2016.03.009.T003:表3 不同性别调查对象各年龄组骨骼肌肉量下降率比较[%(n)]

    10.3760/cma.j.issn.0253-9624.2016.03.009.T003:表3 不同性别调查对象各年龄组骨骼肌肉量下降率比较[%(n)]

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